Check out our new preprint on stress-induced reinstatement of Pavlovian alcohol seeking!

Our new preprint on the effect of stress on responses to extinguished alcohol cues is available here. This manuscript was prepared for a special journal issue honoring Dr. Nadia Chaudhri, whose work on context-induced reinstatement of Pavlovian alcohol seeking inspired these experiments. We examined the impact of three stressors that have been shown to reinstate operant responding for alcohol reward: yohimbine (a pharmacological stressor), intermittent footshock, and an odor cue previously paired with social defeat. We found that yohimbine reinstated both alcohol and sucrose seeking in a Pavlovian setting, but footshock and a social defeat cue failed to enhance alcohol seeking behavior.

Screenshot of bioRxiv header for the paper.
Jocelyn Richard